Hugh Roy and Lillie Cranz Cullen Endowed Professor
Her research focuses on utilizing novel proteomic technologies including ITRAQ and NRM assays to quantitate biomarkers in human body fluids. Other research interests include detecting novel biomarkers in human body fluids using Somalogic’s SomaScan Assay.
Her research focuses on working with animal models and mouse colony management.
Rajalakshmy Ayilam Ramachandran
Raja’s current research is to understand the cellular and molecular mechanisms behind
lupus nephritis, inflammatory bowel disease, neuroinflammation, and Sjögren’s syndrome.
Clinical Research Fellow
Ting, a rheumatologist in China, research focuses on the discovery of novel biomarkers for Lupus Nephritis and primary Sjogren Syndrome to improve the early diagnosis and subsequent evaluation.
Hao is a visiting scholar from China, focusing on the stool protein biomarkers of colorectal cancer.
Qiang Wang, M.D., Ph.D.
Qiang is a visiting scholar from China. He will work on the effect of CDC42 on macrophage migration and its roles in renal ischemia-reperfusion injury, anti-GBM nephritis and lupus nephritis.
Ding’s research focuses on verifying the anti-inflammatory effects of the peptoid GUCM-1, as well as performing cell-SELEX to identify the aptamers that can bind with the B lymphocyte cells.
Her research focuses IL1B signaling pathway and neutrophilic activity on the using transgenic zebrafish models. She also explores the potential to enhance immune cell viability and functionality by using advanced 3D artificial scaffolds derived from decellularized organs and natural polymers.
She currently has two projects, one is Lupus self-diagnosis: development of a lateral flow assay for active LN and the other is microrobots target cancer cell under electromagnets to fulfill drug delivery task.
His research focuses on the application of Machine Learning and Artificial Intelligence techniques in the field of medicine. Currently, he’s working on a deep learning algorithm that aims to accurately diagnose SLE from IHC/IF data collected from various healthcare institutions.
Her research focuses on testing of suitable 3D environments for the growth of immune cells.
Ferial is working on designing a rheumatic diseases biomarker panel for early diagnostic testing. She is also working on another early diagnostic method for chronic myeloid leukemia using ELISA and electro-chemiluminescent platforms.
Ramya’s work mainly focuses on validating biomarkers associated with inflammatory bowel disease (IBD) in stool samples and disease groups within the lupus nephritis population. She also works for Houston Omics Collaborative.
Omar’s research focuses on immunohistochemistry for staining various antibodies on mice kidneys, as well as optimizing IHC protocol. With collaborators, Omar’s project focuses on imaging various immune cells using IR microscopy.
Malavika is a biomedical engineering student whose research focuses on the validation of biomarkers identified in microarray and elevated in IBD stool samples in order to make treatment more efficient for this disease. Her other focuses are testing buffers for stool extraction and ELISA validation for microarray urine samples.
Mallika’s research focuses on manipulating the interaction between Fatty Acid Amide Hydrolase (FAAH), an integral membrane protein high in cancer cells, and naturally-produced endocannabinoids to induce apoptosis as a possible therapeutic alternative to chemotherapy. Mallika was awarded the Provost Undergraduate Research Scholarship (PURS) for Spring 2020.
Pooja’s research focuses on screening cancer patient urine samples to identify potential urine biomarkers that were present in elevated levels by using aptamer based screening as well as Luminex screening.
Anjali’s research focuses on analyzing protein biomarkers in inflammatory bowel disease (IBD) plasma samples through the use of aptamer based screening and ELISA validation.
Phuongthy T Tran
Phuongthy was awarded the Summer Undergraduate Research Fellowship (SURF) for Summer 2020. Her project was a literature review of the top ten themes of systemic lupus erythematosus with a focus on environmental and genetic factors. She is also helping to develop a lupus tracking app that can be used in future clinical research.
Rani’s research focuses on ALCAM (CD166), a protein biomarker, and the mechanism by which it promotes the development of lupus nephritis. She also explores the molecular mechanisms of BANK1, the disease gene for SLE, to determine how the gene promotes autoimmunity.
Nhi is currently working on immunohistochemistry to identify specific genes on specific tissues of the mouse’s kidney such as CD31 in order to compare the difference in tissue structure and gene expression between the healthy mouse and the lupus mouse.
Shereen was awarded the Summer Undergraduate Research Fellowship (SURF) for Summer 2020. Shereen’s project focused on conducting an aptamer-based screening of cancer-based urine samples for 1300 unique proteins. The analysis was conducted for the samples, to distinguish between groups including bladder cancer versus healthy control samples, low stage bladder cancer versus high stage bladder cancer samples, and prostate cancer versus bladder cancer samples. Approximately 26 protein biomarkers have been selected for ELISA validation, in hopes to find significant urinary biomarkers for bladder cancer.
Malikah Al Alshaikh
Rose Ann Huynh
Visiting Research Scholars
Aurélie De Groof
Eric Zhiyan Liang
High School Students/Interns
Sai Harish Dharmavaram
Jae Won Joh